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Molecule Targeting Chlamydia Identified, Paving Way for Precision Antibiotics

  • On May 8, 2025, scientists from Umeå University and Michigan State University identified a molecule capable of targeting and eliminating chlamydia bacteria while leaving the helpful bacteria vital for health unaffected.
  • The team used a multi-strategy antimicrobial discovery approach to find molecules targeting Chlamydia trachomatis, aiming to overcome increasing antibiotic resistance and microbiome disruption.
  • Chlamydia often causes mild or no symptoms but untreated infections can lead to infertility, chronic pelvic pain, and increased cancer risks, affecting about 130 million people globally each year.
  • The researchers identified over 60 promising compounds, isolating a potent one that disrupts chlamydia’s fatty acid synthesis, with Barbara Sixt noting this may prove very important for developing effective and gentle antibiotics.
  • This discovery marks a milestone toward precision antibiotics for chlamydia, suggesting new treatments that spare beneficial bacteria while addressing urgent global needs amid growing resistance, though further research is still required.
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Technology Networks broke the news in on Thursday, May 8, 2025.
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