Targeting Brain Neurons to Successfully Treat Type 2 Diabetes

Targeting brain neurons to successfully treat type 2 diabetes

Successfully treating type 2 diabetes may involve focusing on brain neurons, rather than simply concentrating on obesity or insulin resistance, according to a study published today in the Journal of Clinical Investigation.

Can the brain be targeted to treat type 2 diabetes?

Successfully treating type 2 diabetes may involve focusing on brain neurons, rather than simply concentrating on obesity or insulin resistance, according to a study published today in the Journal of Clinical Investigation.

Surprising Diabetes Fix Found in the Brain

New research reveals that hyperactivity in a specific set of brain cells, AgRP neurons in the hypothalamus, plays a key role in type 2 diabetes—independent of obesity. When these neurons were silenced in diabetic mice, blood sugar normalized for months, even without changes in weight or food intake. This challenges long-standing beliefs that obesity and insulin resistance are the sole drivers of diabetes.

Targeting the Brain: A New Frontier in Treating Type 2 Diabetes

In a groundbreaking study published in the Journal of Clinical Investigation, researchers from the University of Washington have unveiled an unexpected piece in the complex puzzle of type 2 diabetes management. Their new findings suggest that the underlying cause and potential treatment pathways for this widespread metabolic disorder may lie not solely within the conventional realms of obesity and insulin resistance, but rather deep within a spe…