2025 Crosstown Classic: Schedule, pitching matchups and more as Cubs, White Sox square off at Wrigley Field this weekend

White Sox and Cubs square off at Wrigley Field leads Friday's TV schedule

White Sox and Cubs square off at Wrigley Field leads Friday's TV schedule.

2025 Crosstown Classic: Schedule, pitching matchups and more as Cubs, White Sox square off at Wrigley Field this weekend

CHICAGO — The 2025 Crosstown Classic is back to a six-chapter affair. Following three seasons of playing each other just four times each — two games at each ballpark — due to some MLB scheduling changes, the Cubs and White Sox are back to playing six games against each other for the first time since 2021 in this season's Crosstown Classic. Cubs vs. White Sox history: A World Series, the City Series and the Crosstown Classic — a look at Chic…

Chicago baseball report: City Series starts Friday at Wrigley Field for the Cubs and White Sox

A soft part in the Cubs’ schedule continues this weekend as they face off against the White Sox, who own the worst record in the American League. Cade Horton will make his first MLB start Friday as the City Series opens. The Cubs then hit the road for a six-game road series in Miami and Cincinnati before returning home to play MLB’s worst, the Colorado Rockies, and another three-game set versus the Reds. The City Series begins a stretch of nine …

Table of ContentsMiguel Vargas shakes home run and drives ChicagoVargas produces for the second game followed in MLB 2025 The Cuban big leagues Miguel Vargas unloaded all his strength with the stake through a quadrangular that opened the slate in the engagement developed by Chicago White Sox and Chicago Cubs in the afternoon of Friday May 16, 2025 on another day of MLB. From the pitch of the Wrigley Field was held this first duel of the weekend …

Chi. White Sox vs Chi. Cubs MLB Props & Picks on Kyle Tucker

Chi. White Sox (14-30) at Chi. Cubs (25-19) When: May 16 2025, 2:20 PM Where: Wrigley Field, Chicago Where to watch: MLBN Game Odds, Spread, Moneyline & Total Chicago White Sox @ Chicago Cubs Moneyline Chicago White Sox   +185 Chicago Cubs   -225 Chicago White Sox @ Chicago Cubs Runline Chicago White Sox   1.5 (-110) Chicago Cubs   -1.5 (-110) Chicago White Sox @ Chicago Cubs Total Over   11.5 (-115) Under   11.5 (-105) Props source: MyBookie …

MLB Gameday: White Sox at Cubs, Probable Pitchers, Lineups, and more

Follow MLB results with FREE live box scores, starting probable pitchers today, strikezone info, and Statcast data for White Sox vs. Cubs at Wrigley Field