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HIV drugs found to significantly reduce Alzheimer's risk in new study

  • Researchers at the University of Virginia found that patients taking HIV drugs called NRTIs had a significantly lower risk of developing Alzheimer's disease by 2025.
  • The research team analyzed over 270,000 patients' health records from two major U.S. Databases and adjusted for confounding factors like pre-existing conditions.
  • NRTIs appear to reduce Alzheimer's risk by calming brain inflammation, differing from existing treatments targeting protein buildups, with a safer drug called K9 also developed for trials.
  • Data showed a 6% to 13% annual decrease in Alzheimer's risk per year of NRTI use, and the drugs could prevent about 1 million new Alzheimer’s cases annually if confirmed.
  • These findings suggest NRTIs warrant clinical testing for Alzheimer's prevention and could offer a new treatment direction amid rising dementia rates and care costs.
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The Suncoast News & Scoop broke the news in on Thursday, May 8, 2025.
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