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Human Antibodies Drive Breakthrough in Broad-Spectrum Snake Antivenom

  • Researchers led by Peter Kwong at Columbia University published in 2025 a study on a broad-spectrum antivenom using antibodies from Tim Friede's blood.
  • This research followed media reports in 2017 about Friede, who injected himself with snake venom for nearly 18 years to develop natural immunity.
  • The antivenom neutralized venom from 19 snake species in mice, mainly targeting elapids common in Australia where field research is planned.
  • Kwong said the final product could be a single pan-antivenom or two targeting elapids and viperids, while experts caution the antivenom is untested in humans.
  • This development suggests potential for safer, broader snakebite treatments, addressing the WHO-recognized need amid about 110,000 annual snakebite deaths worldwide.
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Nature broke the news in United Kingdom on Friday, May 2, 2025.
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