Psilocybin better preserves depressed patients' emotional response to music than standard drug, study finds
- A study published in Molecular Psychiatry compared psilocybin and escitalopram effects on emotional responses in depressed patients using music as a stimulus.
- Researchers aimed to understand how psilocybin or escitalopram affects emotional and reward processing in patients diagnosed with major depressive disorder.
- The study found that psilocybin better preserved or enhanced emotional responsiveness during pleasurable experiences like music, while escitalopram often blunted it, despite similar clinical improvements.
- Rebecca Harding, first author, said music is an ideal tool to examine affective processing and that these findings have important implications for patients' emotional lives.
- These results suggest psilocybin could restore emotional responsiveness more effectively than some antidepressants, indicating a need for further studies to validate this potential.
11 Articles
11 Articles
Psilocybin better preserves depressed patients' emotional response to music than standard drug, study finds
Depression is among the most widespread mental health disorders worldwide, typically characterized by persistent feelings of sadness, a lack of interest in daily activities and dysregulated sleep and/or eating habits. There are now a wide range of pharmacological treatments for depression, including selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants and atypical antide…
Washington cities are decriminalizing magic mushrooms. Could a psychedelic ‘renaissance’ take hold statewide?
Resolutions have decriminalized psilocybin in cities across Western Washington. Studies show psychedelics can help people suffering from trauma, depression, and anxiety. And more people are microdosing for their mental health.
Psilocybin effectively reduces symptoms of depression, study finds
A study found that high doses of psilocybin led to a significant reduction in depressive symptoms, with effects observed from the first treatment and sustained over several weeks. The 2024 trial, published in the American Journal of Psychiatry, investigated the effects of psilocybin for severe, treatment-resistant depression. — Read the rest The post Psilocybin effectively reduces symptoms of depression, study finds appeared first on Boing Boing.
A single dose of psilocybin might help reduce symptoms in treatment-resistant depression
A new open-label study suggests that a single dose of psilocybin, combined with psychological support, may reduce symptoms in people with severe treatment-resistant depression. Improvements were sustained for up to 12 weeks, although effects were weaker in those with PTSD.
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