US EditionMultiple laboratory techniques can provide a wealth of knowledge about brain cancer
- Researchers published two studies revealing detailed cellular and genetic insights into glioblastoma using advanced single-cell sequencing techniques in 2025.
- They conducted retrospective analyses of tumor samples collected at diagnosis and recurrence to understand tumor evolution and heterogeneity over time.
- The studies identified three recurring tumor ecosystems with distinct cell types, found patient-specific evolutionary paths driven partly by treatment, and linked hypoxia to therapy resistance.
- Kevin Johnson said the approach provides a richer view of tumor biology by sampling a tumor region about the size of a ping pong ball, allowing inference of cell function.
- These findings lay groundwork for new diagnostics and treatments but require further research and clinical translation before routine clinical use.
12 Articles
12 Articles
Combining laboratory techniques yields wealth of information about deadly brain tumors
Clinicians have demonstrated that doctors can gain a wealth of knowledge about a patient's cancer by using multiple laboratory techniques to study tumor tissue taken from needle biopsies of glioblastoma, a highly aggressive form of brain cancer.
Multiple laboratory techniques can provide a wealth of knowledge about brain cancer
Clinicians from the Johns Hopkins Kimmel Cancer Center and four other institutions have demonstrated that doctors can gain a wealth of knowledge about a patient's cancer by using multiple laboratory techniques to study tumor tissue taken from needle biopsies of glioblastoma, a highly aggressive form of brain cancer.
Targeting the glioblastoma resection margin with locoregional nanotechnologies
Surgical resection is the first stage of treatment for patients diagnosed with resectable glioblastoma and is followed by a combination of adjuvant radiotherapy and systemic single-agent chemotherapy, which is typically commenced 4–6 weeks after surgery. This delay creates an interval during which residual tumour cells residing in the resection margin can undergo uninhibited proliferation and further invasion, even immediately after surgery, thu…
Gabapentinoids Improve Survival in Human Glioblastoma
In a groundbreaking study poised to shift the paradigm of glioblastoma treatment, researchers have unveiled compelling evidence that gabapentinoids, a class of drugs traditionally employed in neuropathic pain and seizure management, confer a significant survival advantage in human glioblastoma patients. This revelation arises from an extensive, multifaceted investigation that meticulously combines clinical data, molecular biology, and pharmacolo…
USP18 Enhances SOX9 to Drive Glioblastoma Growth
In the relentless quest to unravel the complex mechanisms underlying glioblastoma—the most aggressive and lethal form of brain cancer—new research has spotlighted a critical molecular interplay that fuels tumor progression and stemness. A recent breakthrough study has identified the enzyme USP18 as a pivotal regulator that deubiquitinates and stabilizes the transcription factor SOX9, thereby sustaining the malignant traits and resilience of glio…
Gabapentin & Glioblastoma Survival: New Findings – Archyde: Latest World News, Economy, Entertainment, Health, Technology & Sports Updates
Archyde: Latest World News, Economy, Entertainment, Health, Technology & Sports Updates Gabapentin: A Surprising Ally in the Fight Against Glioblastoma? glioblastoma (Gbm), the most aggressive form of brain cancer, continues to challenge medical science. But a recent study offers a glimmer of hope: could gabapentin, a widely prescribed anti-seizure medication, hold the key to extending survival for patients battling this devastating disease? Thi…
Coverage Details
Bias Distribution
- 100% of the sources are Center
To view factuality data please Upgrade to Premium
Ownership
To view ownership data please Upgrade to Vantage
