New research on ALS opens up for early treatment

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Funding for research on ALS and other diseases must not be halted

Researchers are being hampered by Trump administration cuts.

Despite terminal illness, Niagara’s Steve Gallagher never gave up fight for ALS treatment, research

The journalist, publicist and Niagara ALS Warrior has died of Lou Gehrig's disease at 52.

New research on ALS opens up for early treatment

Using the gene scissors CRISPR and stem cells, researchers have managed to identify a common denominator for different gene mutations that all cause the neurological disease ALS. The research shows that ALS-linked dysfunction occurs in the energy factories of nerve cells, the mitochondria, before the cells show other signs of disease, which was not previously known.

Medications that suppress REM sleep improve survival in amyotrophic lateral sclerosis patients

During REM sleep, the body enters a state of paralysis. This can pose a danger for patients with weakened diaphragms due to neuromuscular diseases. Now new research published at the ATS 2025 International Conference has shown that antidepressants that suppress REM sleep are associated with improved survival in people with amyotrophic lateral sclerosis (ALS).

The drug has been tested with a rare form of ALS caused by a mutation in a gene called FUS, which is responsible for between 1% and 2% of cases of the disease, but which causes some of the most aggressive forms and begins in adolescents and young adults.