Noninvasive prenatal testing identifies twice as many Down syndrome cases as second-trimester serum screening

Prenatal Genetic Testing and Screening: Constructing Needs and Reinforcing Inequities | American Journal of Law & Medicine

Prenatal Genetic Testing and Screening: Constructing Needs and Reinforcing Inequities - Volume 17 Issue 1-2

Noninvasive prenatal testing identifies twice as many Down syndrome cases as second-trimester serum screening

A novel study has analyzed the cost-effectiveness of different Down syndrome (DS) screening strategies. The result confirms that noninvasive prenatal testing (NIPT) outperforms second-trimester serum screening (STSS) in accuracy and cost-effectiveness, as NIPT identifies twice as many DS cases as STSS.

Down Syndrome Detection Doubled with NIPT over STSS

A new study by researchers in China has found that non-invasive prenatal testing (NIPT) detects twice as many cases of Down syndrome (DS) as second-trimester serum screening (STSS), while also being more cost-effectiveness. The study, published in the journal Frontiers in Public Health, was a retrospective analysis of clinical data from more than 140,000 pregnant women who underwent both NIPT and STSS testing to analyze the sensitivity, specific…