Novel Role for Disordered Protein in Coordinating Key Stages of Gene Expression

A recent study published in Cell Reports by a team of researchers at the University of Freiburg has revealed a new aspect on the function of a protein in the regulation of genetic expression. In this paper, the role of TAF2 is analyzed, a component of the general transcription factor TFIID, in the connection between the reading of genes and the editing of their RNA products. TAF2 contains an intrinsic disordered region (IDR), which acts as a pos…

Novel Role for Disordered Protein in Coordinating Key Stages of Gene Expression

Research reveals TAF2's disordered region links transcription and RNA editing, highlighting its role in gene expression regulation and nuclear organization.