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Emotions and Brain Function Are Altered up to One Month After a Single High Dose of Psilocybin

Summary by Nature
Psilocybin is a classic psychedelic compound that may have efficacy for the treatment of mood and substance use disorders. Acute psilocybin effects include reduced negative mood, increased positive mood, and reduced amygdala response to negative affective stimuli. However, no study has investigated the long-term, enduring impact of psilocybin on negative affect and associated brain function. Twelve healthy volunteers (7F/5M) completed an open-la…

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researchsquare.com broke the news in on Thursday, May 15, 2025.
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