US EditionReprogramming site-specific retrotransposon activity to new DNA sites
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Reprogramming site-specific retrotransposon activity to new DNA sites
Retroelements have a critical role in shaping eukaryotic genomes. For instance, site-specific non-long terminal repeat retrotransposons have spread widely through preferential integration into repetitive genomic sequences, such as microsatellite regions and ribosomal DNA genes1–6. Despite the widespread occurrence of these systems, their targeting constraints remain unclear. Here we use a computational pipeline to discover multiple new site-spec…
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