Childhood brain tumors develop early in highly specialized nerve cells

Childhood brain tumors develop early in highly specialized nerve cells

Medulloblastomas, brain tumors in children, are thought to develop between the first trimester of pregnancy and the end of the first year of life. Researchers have now analyzed the genetic changes of each individual cancer cell in tumor samples in order to reconstruct which genetic changes occur first during tumor development and when.

Specialists from CONICET, the National University of Córdoba (UNC) and the Private University Hospital of Córdoba identified a promising new therapeutic target for patients with a type of pituitary tumor where 50 percent of patients do not respond adequately to current treatments. The progress is described in the journal Neuro oncology. The pituitary is an organ located at the base of the brain that makes hormones to control other glands and man…

Rewrite Childhood brain tumors develop early in highly specialized nerve

Medulloblastoma is one of the most common malignant tumors of the central nervous system (CNS) in children and adolescents. It develops in the area of the cerebellum, which is responsible for movement coordination, among other things. Medulloblastomas enlarge rapidly, often grow into surrounding tissue and can also form metastases. The wide variety of this tumor group also makes it difficult to find the right treatment. A team of researchers at …