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Weight-loss drugs may lower cancer risk in people with diabetes, a study suggests

  • A study led by Lucas Mavromatis at NYU's Grossman School of Medicine found that GLP-1 drugs lowered obesity-related cancer risk in adults with diabetes.
  • Researchers analyzed 170,000 patient records and compared those who took GLP-1 receptor agonists to those who took other diabetes drugs not linked to weight loss.
  • After four years, the GLP-1 group had a 7% lower risk of obesity-related cancers and 2,501 new cancer cases versus 2,671 in the comparison group, with effects seen mainly in women.
  • Dr. Ernest Hawk, not involved in the study, called for more research to confirm these findings, noting this study cannot establish cause and effect but suggests a connection worth exploring.
  • The study, supported by the NIH and shared at the annual meeting of the American Society of Clinical Oncology, suggests that widely used weight-loss medications such as Wegovy and Ozempic may help reduce the risk of certain obesity-related cancers.
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Weight-loss drugs may lower cancer risk in people with diabetes, a study suggests

Researchers are beginning to wonder if blockbuster drugs like Wegovy, Ozempic and Zepbound could play a role in preventing cancer.

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Sci Tech Daily broke the news in on Wednesday, May 21, 2025.
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