Clinical-grade whole genome sequencing-based haplarithmisis enables all forms of preimplantation genetic testing

Clinical-grade whole genome sequencing-based haplarithmisis enables all forms of preimplantation genetic testing

High-throughput sequencing technologies have increasingly led to discovery of disease-causing genetic variants, primarily in postnatal multi-cell DNA samples. However, applying these technologies to preimplantation genetic testing (PGT) in nuclear or mitochondrial DNA from single or few-cells biopsied from in vitro fertilised (IVF) embryos is challenging. PGT aims to select IVF embryos without genetic abnormalities. Although genotyping-by-sequen…

Sen. Hicks wins Senate approval for rapid whole-genome sequencing for vulnerable children

Sen. Hicks wins Senate approval for rapid whole-genome sequencing for vulnerable children maliabennett Thu, 05/08/2025 - 15:32 OKLAHOMA CITY – Sen. Carri Hicks has won full Senate approval for a bipartisan measure increasing access to rapid whole-genome sequencing (rWGS) for critically ill infants. Assistant Democratic Leader Hicks, D-Oklahoma City, is the Senate principal author of House Bill 1567, and House Majority Leader Mark Lawson, R-Sapu…