Viruses under the super microscope: How influenza viruses communicate with cells

Single influenza A viruses induce nanoscale cellular reprogramming at the virus-cell interface

During infection, individual virions trigger specific cellular signaling at the virus-cell interface, a nanoscale region of the plasma membrane in direct contact with the virus. However, virus-induced receptor recruitment and cellular activation are transient processes that occur within minutes at the nanoscale. Hence, the temporal and spatial kinetics of such early events often remain poorly understood due to technical limitations. To address t…

Viruses under the super microscope: How influenza viruses communicate with cells

Influenza viruses are among the most likely triggers of future pandemics. A research team has developed a method that can be used to study the interaction of viruses with host cells in unprecedented detail. With the help of their new development, they have also analyzed how novel influenza viruses use alternative receptors to enter target cells.

Influenza viruses are among the most likely triggers of future pandemics. A research team of the Helmholtz Centre for Infection Research (HZI) and the University Hospital Freiburg has developed a method with which the interaction of viruses with host cells at a unique depth of detail under...