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Top National Institutes of Health (NIH)… News

Science

Neuroinflammation across neurological diseases

The brain's response to injury includes the activation of intrinsic microglia and the influx of leukocytes, collectively constituting neuroinflammation, the "flame" of the brain. Although details differ and matter, neuroinflammation exacerbating neurodegeneration has similarities across multiple scl …Read Article

Science

In vivo CAR T cell generation to treat cancer and autoimmune disease

Chimeric antigen receptor (CAR) T cell therapies have transformed treatment of B cell malignancies. However, their broader application is limited by complex manufacturing processes and the necessity for lymphodepleting chemotherapy, restricting patient accessibility. We present an in vivo engineerin …Read Article

Science

Association between fruit intake and abdominal adiposity in 1,707 randomly selected U.S. children

This investigation was conducted to determine the relationship between fruit intake and abdominal adiposity in 1,707 U.S. children. The children were randomly selected as part of the National Health and Nutrition Examination Survey (NHANES), so the ...Read Article

Carcinogenic effects of long-term exposure from prenatal life to glyphosate and glyphosate-based herbicides in Sprague-Dawley rats

Glyphosate and GBHs at exposure levels corresponding to the EU ADI and the EU NOAEL caused dose-related increases in incidence of multiple benign and malignant tumors in SD rats of both sexes. Early-life onset and mortality were observed for multiple tumors. These results provide robust evidence sup …Science Read Article

Functional brain network correlates of cardiorespiratory fitness and moderation by depression symptoms

Cardiorespiratory fitness may protect against or alleviate depression through neuroplastic mechanisms within disrupted brain networks underlying cognitive and affective symptoms. There is a scarcity of research examining the effects of ...Science Read Article

Ultrapotent SARS coronavirus-neutralizing single-domain antibodies that clamp the spike at its base

Therapeutic monoclonal antibodies can prevent severe disease in SARS-CoV-2 exposed individuals. However, currently circulating virus variants have evolved to gain significant resistance to nearly all neutralizing human immune system-derived therapeutic monoclonal antibodies that had previously been …Science Read Article

Kirigami-Inspired Breathable Smart Contact Lens for Wireless Monitoring of Corneal Hypoxia and Microenvironment

Severe corneal dysfunctions caused by corneal hypoxia and microenvironmental imbalance threaten hundreds of millions of people's eye health, leading to neovascularization, keratitis, and even vision loss, particularly among contact lens wearers. However, there are no accessible digital tools for wea …Read Article

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Top National Institutes of Health (NIH)… News

Neuroinflammation across neurological diseases

In vivo CAR T cell generation to treat cancer and autoimmune disease

Association between fruit intake and abdominal adiposity in 1,707 randomly selected U.S. children

Carcinogenic effects of long-term exposure from prenatal life to glyphosate and glyphosate-based herbicides in Sprague-Dawley rats

Functional brain network correlates of cardiorespiratory fitness and moderation by depression symptoms

Ultrapotent SARS coronavirus-neutralizing single-domain antibodies that clamp the spike at its base

Kirigami-Inspired Breathable Smart Contact Lens for Wireless Monitoring of Corneal Hypoxia and Microenvironment

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